2025 Genentech Road Acquisition Project
June 25, 2025
City Council Presentation
Genentech Campus Boundary
2 Acquired / Controlled Parcels
3 3
525 DNA
Way
383-93 E Grand
Ave
333 Pt San
Bruno Blvd
Proposed Genentech Boundary
4 5
Genentech Road Network
5 6
Genentech Campus Master Plan
6 Potential DNA
Way Closure
Area
Genentech Campus Vehicle Access / Closure
7 Genentech Entitlements
Required Entitlements
• Street Vacations
• Purchase and Sale Agreement
• Genentech Campus Master
Plan Amendments
• General Plan Amendments
• Zoning Map Amendments
• Approval of Addendum
Genentech Entitlements
9 Proposed Street Vacations
• DNA Way (shown in orange)
• Cabot Road (shown in blue)
• Point San Bruno Blvd (shown in
green)
Street Vacations
10 Proposed Terms
• $20M for Orange Section
• $5M for Green, Blue and Pink
Sections
• Maintenance and License
Agreement
• Outlines ongoing maintenance
obligations, provides for
reimbursement of City for 5-year
period
• City granted necessary public
utility easements
Purchase and Sale Agreement
11 Genentech Campus Public Access
12 Proposed Amendments within:
• Chapter 3: Urban Design
• Chapter 4: Transportation, Circulation and Parking
• Figures throughout the document
Also memorializes obligations related to future
appraisals and requirements prior to terminating
public access.
Genentech Master Plan Amendments
13 General Plan Amendments
14 1414
Show Figures
Zoning Map Amendments
15 Addendum to 2000 Genentech EIR & 2040 GP EIR
• No new campus development
• No new operations
• Genentech not requesting increase in potential
Campus buildout assumed in 2020 Genentech EIR
Project will not cause any new or substantially
more significant environmental impacts
Environmental Review
16 Planning Commission reviewed on May 15, 2025
• Would City be setting a precedent by selling
public roads to a private entity?
• How would the vacated roads be assessed for
tax purposes?
• How much money would the City be saving by
divesting in these three public roads?
The Commission found that the vacation of the
streets is in conformance with the SSF General Plan,
and recommended approval of all entitlements by
a vote of 5-0
Planning Commission Review
17 Planning Commission recommends that Council:
1. Move to adopt a resolution making a CEQA determination;
2. Move to adopt a resolution vacating DNA Way;
3. Move to adopt a resolution vacating Point San Bruno Blvd;
4. Move to adopt a resolution vacating Cabot Road within the Genentech Campus Master Plan boundaries;
5. Move to adopt a resolution approving the sale of DNA Way, Point San Bruno Blvd and Cabot Road to Genentech in the sum of $25M and associated Purchase and Sale Agreement;
6. Waive reading and introduce an ordinance amending the SSF Zoning Map; and
7. Move to adopt a resolution approving Planning entitlements.
City Council Recommendation
18 2025 Genentech Road Acquisition Project
THANK YOU